EFFECT OF TWEEN 80 ON THE STABILITY AND CONFORMATION OF TELOMERIC G-QUADRUPLEX DNA
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lviv Polytech Natl Univ
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
G-quadruplex DNA is formed in telomer. It inhibits telomerase enzyme which is found active in more than 85 % of cancer cells. In this work, the effect of Tween 80 on telomeric G-quadruplex DNA, AGGG(TTAGGG)3 was studied using circular dichroism spectroscopic technique. The obtained results showed that using Tween 80 with telomeric quadruplex is safe up to less than 1.0 %.
Açıklama
Anahtar Kelimeler
telomere, quadruplex, Tween 80, circular dichroism, conformation
Kaynak
Chemistry & Chemical Technology
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
17
Sayı
3
